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RYTM Rhythm Pharmaceuticals Inc

NASDAQ
Health Care
Biotechnology

$86.46

▼ 1.7%

Updated Oct 16, 2:25 PM ET

Report Card

RYTM at a glance — five pillars scored 0–100 from real filed financials.

How the 0–100 rating is calculated
Value
—
Growth
—
Profitability
0
Health
100
Dividends
—

Overall: not rated yet. This stock's fundamentals ratios aren't loaded, so only the pillars its filings support are scored.

Key Metrics

Market Cap

—

P/E

—

Forward P/E (est.)

—

ROE

—

Revenue Growth

—

EPS Growth

—

Profit Margin

—

FCF Yield

—

Debt / Equity

—

ROIC

-86.0%

Interest Coverage

—

Current Ratio

3.45x

Dividend Yield

—

Implied Growth (rev. DCF)

—

Rating Score

Not rated

Business Overview

Research

Rhythm Pharmaceuticals Inc (RYTM) is a NASDAQ-listed company in the Biotechnology industry, within the Health Care sector.

In its latest reported year it generated about $189.76M in revenue and posted a net loss of $196.54M.

Our model hasn't rated RYTM yet because its fundamentals ratios (P/E, margins, returns on capital, leverage) aren't loaded. Any financial history below comes straight from its SEC filings and refreshes automatically.

Economic Moat

Evidence of durable competitive advantage in the filed financials (5 years of history).

Profit margins and economic moats, explained
No moat evidenceMoat evidence score: 25/100

The numbers don't show a durable competitive advantage — margins, growth, or returns on capital have been unstable or thin. Great returns are still possible; they just aren't protected.

Operating margin level0/100

-181.1% average over the last 3 years

Operating margin stability0/100

±2039.4 pts around -1338.6% across 5 years

Revenue durability100/100

grew in 4 of the last 4 year-over-year periods

Free-cash-flow consistency0/100

positive in 0 of 5 years

Return on invested capital0/100

-86.0% latest fiscal year

A moat can't be proven by numbers alone — this scores the evidence a durable advantage leaves behind (pricing power, consistency, returns on capital), computed the same way for every stock. Pair it with the business overview before concluding anything.

Revenue Growth

Research
How to read an income statement

4Y CAGR

178.5%

Revenue moved from $3.15M in 2021 to $189.76M in 2025, a 178.5% compound annual growth rate. The most recent year was roughly steady year over year. Slower, mature growth is common for established businesses.

0/1 checks passedROIC above 10%

Gross Margin

—

Operating Margin

-101.2%

Net Margin

-103.6%

ROE

—

Debt Analysis

Research
1/1 checks passedShort-term bills covered

Total Debt

$72.96M

Net Debt

$7.35M

Net Debt / EBITDA

—

Debt / Equity

—

Leverage: debt-to-equity is n/a, with a current ratio of 3.5x. Detailed balance-sheet leverage is limited for this name. It carries roughly $72.96M of total debt against $65.61M of cash.

Cash Flow Analysis

Research

Operating CF

-$115.67M

Free Cash Flow

-$116.63M

FCF Margin

-61.5%

In the latest year Rhythm Pharmaceuticals Inc produced about -$115.67M of operating cash flow but negative free cash flow as it invested heavily. Cash flow is what ultimately pays shareholders, so it is worth tracking over time.

Valuation Analysis

Research
What is a reasonable P/E ratio?

P/E

—

P/S

—

P/B

—

EV / EBITDA

—

RYTM trades at n/a trailing earnings. Its valuation ratios aren't loaded yet, so there is no P/E to judge here.

Metrics vs. Sector Range

Where RYTM sits versus the Health Care companies we cover.

TTM P/E
——
Forward P/E
——
P/S ratio
——
Revenue growth
——
EPS growth
——
Gross margin
——
Net margin
——
ROE
——

Bands show the middle half (25th–75th percentile) of the 83 Health Care companies in our coverage that have fundamentals data — the peer-relative anchor professional comps analysis uses. Context only — not investment advice.

Sector Peer Comparison

How RYTM stacks up against its Health Care peers — valuation, profitability, and growth versus the sector median.

RYTM doesn't have a model rating yet (its fundamentals ratios aren't loaded), so it isn't ranked against the 83 rated Health Care companies we cover.

P/E vs sector

—

median 26.1x

ROE vs sector

—

median 14.1%

Growth vs sector

—

median 7.6%

Sector rank

—

not rated yet

CompanyP/ERev Gr.Rating
RYTMThis stock——Not rated
ABVX——Weak· 35
GMAB20.9x20.7%Favorable· 62
INCY15.7x21.5%Strong· 86
BNTX—-11.8%Weak· 31
MRNA—-30.0%Weak· 17
BIIB25.3x1.2%Neutral· 44
ONC71.9x36.2%Neutral· 48
Health Care median26.1x7.6%52/100

Valuation vs. quality map

sector medianGMABINCYBIIBONCP/E — cheaper ←→ pricierROE — more profitable ↑

The sweet spot is upper-left: more profitable (higher ROE) for a lower P/E. Dashed lines mark the sector median.

Compare side by side

Peers are the closest Health Care companies by sub-industry and size, preferring ones with full data. Sector medians and rank use the 83 rated companies among the 324 Health Care stocks we cover. Educational, not a recommendation.

5-Year Projection Model

Project revenue → earnings → price. Edit the assumptions to build your own case.

What drives this projection, and its limits

2030 scenario price range (Base Case)

$1.46 – $2.43

vs. $86.46 today · implied CAGR -56% – -51%

Metric20262027202820292030
Revenue$204.94M$221.33M$239.04M$258.16M$278.82M
Net income$6.15M$6.64M$7.17M$7.74M$8.36M
EPS$0.09$0.10$0.10$0.11$0.12
Share price (low)$1.07$1.16$1.25$1.35$1.46
Share price (high)$1.79$1.93$2.08$2.25$2.43
CAGR (low–high)-99% / -98%-88% / -85%-76% / -71%-65% / -60%-56% / -51%

Educational scenario model, not a forecast or investment advice. It starts from the latest annual revenue in SEC filings. By default, growth is trailing revenue growth (held between 3% and 45% a year), the net margin is the latest one (held between 3% and 50%, so a loss-making company is modeled with a small profit), and the Base case P/E runs from 60% to 100% of today's. Carrying recent growth forward five years can miss badly in either direction. Outputs are only as good as the assumptions. Growth, margin or P/E data is missing for this stock, so some starting values above are placeholders rather than measurements.

Key Risks

Research

Market risk — sector rotation, the economic cycle, and broad sentiment move the stock regardless of fundamentals.

Analyst Ratings

What 23 Wall Street analysts covering RYTM recommend (September 2026). Consensus is a useful sanity check — not a substitute for your own homework.

Buy
consensus · score 4.2 / 5 across 23 analysts
Strong Buy 8Buy 12Hold 3Sell 0Strong Sell 0

Analysts have turned more cautious over the last three months (-4 pts of buy ratings).

Latest SEC Filings

RYTM's most recent filings, straight from SEC EDGAR. Annual and quarterly reports are the deep dives; 8-Ks flag material events the moment they happen. How to read a 10-K

RYTM — frequently asked questions

Is RYTM a good stock to buy?

We don't give buy or sell advice. Review Rhythm Pharmaceuticals Inc's fundamentals, valuation, and 5-year financials on this page, then make your own decision — and consider a licensed professional.

Where does RYTM's data come from?

Live price data plus the annual financials in Rhythm Pharmaceuticals Inc's SEC filings, refreshed automatically. Its fundamentals ratios aren't loaded yet, which is why it has no model rating.

How is the 5-year projection for RYTM calculated?

It's a scenario model. It starts from the latest annual revenue and net margin in SEC filings, grows revenue at an assumed rate (trailing revenue growth by default), and applies a P/E range built around today's multiple to show the resulting share-price range. When a stock has no growth or P/E data, the starting values are placeholders. It's a tool for thinking, not a prediction.

Is this RYTM analysis financial advice?

No. Everything on this page is educational research, not financial advice or a recommendation to buy or sell RYTM. Always do your own research and consider a licensed professional.

Data notice. Fundamentals and financial statements are sourced from company filings (SEC EDGAR) and market-data providers; prices and market caps refresh on trading days and may be delayed. Ratings, projections, technical signals, and written summaries are model- or rule-generated for education and may simplify or lag the latest filings.

Not advice. Nothing on this page is investment advice or a recommendation to buy, hold, or sell any security. Do your own research and consult a licensed financial professional before investing.