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ONC BeOne Medicines AG

NASDAQ
Neutral · 48/100
Health Care
Biotechnology

$369.34

▼ 1.3%

Updated Oct 16, 2:25 PM ET

Report Card

ONC at a glance — five pillars scored 0–100 from real filed financials.

How the 0–100 rating is calculated
Value
12
Growth
100
Profitability
22
Health
94
Dividends
0

Overall: Neutral · 48/100. A wider, greener shape means more pillars look healthy. Dividends scores 0 when a company pays none — that is a choice, not a flaw.

Price — Past Year

▲ Up 26.4% in the year to Jul 6, 2026

Price 50-day average 200-day averageSource: Yahoo Finance · chart data as of Jul 6, 2026

Key Metrics

Market Cap

$33.43B

P/E

71.88x

Forward P/E (est.)

—

ROE

5.2%

Revenue Growth

36.2%

EPS Growth

—

Profit Margin

7.8%

FCF Yield

—

Debt / Equity

0.25x

ROIC

6.0%

Interest Coverage

—

Current Ratio

3.4x

Dividend Yield

—

Implied Growth (rev. DCF)

6.0%

Rating Score

48/100

Business Overview

Research

BeOne Medicines AG (ONC) is a large-cap NASDAQ-listed company in the Biotechnology industry, within the Health Care sector, with a market value around $33.43B.

In its latest reported year it generated about $5.34B in revenue and $286.93M in net profit.

Our model rates ONC Neutral (48/100) on growth, profitability, financial health, and valuation. The summary below is built from its filed financials and current ratios and refreshes automatically.

Economic Moat

Evidence of durable competitive advantage in the filed financials (10 years of history).

Profit margins and economic moats, explained
Narrow moat signalsMoat evidence score: 57/100

Some durable-advantage evidence, but not across the board — dig into which ingredient is weak and whether it's cyclical or structural.

Gross margin level100/100

85.5% average over the last 3 years

Gross margin stability68/100

±2.6 pts around 84.4% across 5 years

Revenue durability69/100

grew in 7 of the last 9 year-over-year periods

Free-cash-flow consistency0/100

positive in 1 of 10 years

Return on invested capital5/100

6.0% latest fiscal year

A moat can't be proven by numbers alone — this scores the evidence a durable advantage leaves behind (pricing power, consistency, returns on capital), computed the same way for every stock. Pair it with the business overview before concluding anything.

Technical Analysis (Educational)

Research

Technical analysis reads price and volume to judge momentum and timing. It complements the fundamentals above — it does not replace them. Here is what ONC's chart says today, with each tool explained.

Trend — moving averages. A moving average is the average closing price over a window, which smooths out daily noise. ONC trades near $369.34, above its 50-day average ($289.68) and 200-day average ($315.98). Price above both averages, with the shorter one above the longer, is the textbook definition of an uptrend — momentum favours buyers.

Momentum — RSI. The Relative Strength Index runs 0–100 and measures how strong recent gains are versus losses. Above 70 is "overbought", below 30 "oversold". At 83 it is overbought — the recent rally is stretched and can cool off.

MACD. MACD compares two moving averages to flag shifts in momentum. Its histogram is currently positive — short-term momentum is improving.

Volatility — ATR. Average True Range is the typical daily move. ONC's is $9.23 (~2.5% of price), so swings of about that size each day are normal — handy for setting a stop that isn't too tight.

Support & resistance. In the month to Jul 6, 2026, ONC found buyers near $253.95 (support) and sellers near $316.00 (resistance); its 52-week range then was $240.00–$385.22. A decisive break beyond either edge often marks the next move.

Volume. The latest session traded 0.7× the 20-day average — lighter than usual, so the move carries less conviction. Rising volume on up-days suggests real buying; on down-days, real selling.

Educational information to help you read a chart — not a recommendation or a forecast. The indicators were last computed on Jul 6, 2026; the price is current.

Revenue Growth

Research
How to read an income statement

4Y CAGR

46.0%

2/2 checks passedRevenue growingRevenue growth beats sector midpoint

Revenue moved from $1.07M in 2016 to $5.34B in 2025, a 157.6% compound annual growth rate. The most recent year grew a strong 36.2% year over year. Consistent top-line growth is one sign of healthy demand.

Profitability

Research
What profit margins tell you
1/4 checks passedProfitableNet margin above sector midpointROE above 12%ROIC above 10%

Gross Margin

87.5%

Operating Margin

8.4%

Net Margin

5.4%

ROE

5.2%

BeOne Medicines AG keeps about 7.8% of each sales dollar as net profit, with a 87.5% gross margin and 8.4% operating margin. Return on equity is 5.2% and return on invested capital about 6.0%. Margins are moderate — typical of a competitive but profitable business.

Debt Analysis

Research
3/3 checks passedDebt under 1× equityDebt under 2× equityShort-term bills covered

Total Debt

$788.68M

Net Debt

-$4.31B

Net cash position

Net Debt / EBITDA

-9.64x

Debt / Equity

0.25x

Leverage: debt-to-equity is 0.3x, with a current ratio of 3.4x. That is a conservative balance sheet — a cushion in downturns. It carries roughly $788.68M of total debt against $5.10B of cash.

Cash Flow Analysis

Research
1/1 checks passedMarket expects achievable growth (<8%)

Operating CF

$1.13B

Free Cash Flow

$941.74M

FCF Margin

17.6%

In the latest year BeOne Medicines AG produced about $1.13B of operating cash flow and $941.74M of free cash flow after capital spending. Cash flow is what ultimately pays shareholders, so it is worth tracking over time.

Valuation Analysis

Research
What is a reasonable P/E ratio?
1/3 checks passedPositive earnings (P/E meaningful)P/E below sector's upper bandTrading below DCF fair value

P/E

71.88x

P/S

5.96x

P/B

8.65x

EV / EBITDA

49.45x

ONC trades at 71.9x trailing earnings, 6.0x sales, and 8.7x book value. Reverse-engineering today's price implies the market expects roughly 6.0% long-term free-cash-flow growth. That is a rich multiple that prices in a lot of future growth.

DCF Fair Value (Educational)

A two-stage discounted cash flow on real SEC-filed free cash flow — the intrinsic-value anchor professional analysts triangulate from.

How this DCF estimate is calculated

DCF fair value / share

$26.38

Current price

$369.34

-93% · Above fair-value estimate

Starting FCF (latest 10-K)

$941.74M

Growth, years 1–5

20.0%

Fade to terminal, years 6–10

2.5%

Discount rate

9.0%

PV of 10-yr free cash flow$14.55B
PV of terminal value$24.45B
Estimated equity value$39.00B
Shares outstanding1.48B

Cash flows grow at the stage-1 rate (trailing revenue growth, capped at 20%) for five years, fade to 2.5% by year 10, and continue at that rate forever (Gordon terminal value), all discounted at 9.0%. Small changes in assumptions move the result a lot — treat this as one reference point, not a target price. Educational only, not investment advice.

Metrics vs. Sector Range

Where ONC sits versus the Health Care companies we cover.

TTM P/E
71.9xExpensive
Forward P/E
——
P/S ratio
6.0xExpensive
Revenue growth
36.2%Strong
EPS growth
——
Gross margin
87.5%Strong
Net margin
7.8%Average
ROE
5.2%Weak

Bands show the middle half (25th–75th percentile) of the 83 Health Care companies in our coverage that have fundamentals data — the peer-relative anchor professional comps analysis uses. Context only — not investment advice.

Sector Peer Comparison

How ONC stacks up against its Health Care peers — valuation, profitability, and growth versus the sector median.

Among the 83 rated Health Care companies we cover, ONC ranks #50 by our overall rating. It trades at a premium versus the sector on earnings (71.9x P/E vs. 26.1x median) with a lower return on equity (5.2% vs. 14.1%) and faster revenue growth (36.2% vs. 7.6%).

P/E vs sector

71.9x

median 26.1x

ROE vs sector

5.2%

median 14.1%

Growth vs sector

36.2%

median 7.6%

Sector rank

#50

of 83 rated

CompanyP/ERev Gr.Rating
ONCThis stock71.9x36.2%Neutral· 48
BIIB25.3x1.2%Neutral· 44
MRNA—-30.0%Weak· 17
BNTX—-11.8%Weak· 31
INCY15.7x21.5%Strong· 86
ARGX26x80.6%Strong· 88
REGN18.7x5.9%Favorable· 69
GMAB20.9x20.7%Favorable· 62
Health Care median26.1x7.6%52/100

Valuation vs. quality map

sector medianBIIBINCYARGXREGNGMABONCP/E — cheaper ←→ pricierROE — more profitable ↑

The sweet spot is upper-left: more profitable (higher ROE) for a lower P/E. Dashed lines mark the sector median.

Compare side by side

Peers are the closest Health Care companies by sub-industry and size, preferring ones with full data. Sector medians and rank use the 83 rated companies among the 324 Health Care stocks we cover. Educational, not a recommendation.

5-Year Projection Model

Project revenue → earnings → price. Edit the assumptions to build your own case.

What drives this projection, and its limits

2030 scenario price range (Base Case)

$590.53 – $988.79

vs. $369.34 today · implied CAGR 10% – 22%

Metric20262027202820292030
Revenue$7.27B$9.88B$13.44B$18.28B$24.86B
Net income$363.33M$494.12M$672.01M$913.93M$1.24B
EPS$4.01$5.46$7.42$10.10$13.73
Share price (low)$172.62$234.76$319.27$434.21$590.53
Share price (high)$289.03$393.09$534.60$727.05$988.79
CAGR (low–high)-53% / -22%-20% / 3%-5% / 13%4% / 18%10% / 22%

Educational scenario model, not a forecast or investment advice. It starts from the latest annual revenue in SEC filings. By default, growth is trailing revenue growth (held between 3% and 45% a year), the net margin is the latest one (held between 3% and 50%, so a loss-making company is modeled with a small profit), and the Base case P/E runs from 60% to 100% of today's. Carrying recent growth forward five years can miss badly in either direction. Outputs are only as good as the assumptions.

Bull Case

The case for ONC:

  • Revenue is growing 36.2% a year, a sign of real demand.
  • A conservative balance sheet (debt/equity 0.3x) lowers risk.

Bear Case

The case against ONC:

  • A rich 71.9x earnings multiple prices in a lot of growth.
  • Like any single stock, it is exposed to competition, the economic cycle, and shifts in its end markets.

Key Risks

Research

Valuation risk — at 71.9x earnings, disappointing results could compress the multiple.

Market risk — sector rotation, the economic cycle, and broad sentiment move the stock regardless of fundamentals.

Investment Thesis

Research

On balance, the picture is mixed: BeOne Medicines AG is a large-cap health care business still growing nicely, with modest profitability, and a sound balance sheet. It trades at 71.9x earnings, which our model scores Neutral (48/100). Weigh this against your own goals and time horizon — this is educational information, not a recommendation.

Analyst Ratings

What 12 Wall Street analysts covering ONC recommend (September 2026). Consensus is a useful sanity check — not a substitute for your own homework.

Buy
consensus · score 4.2 / 5 across 12 analysts
Strong Buy 3Buy 8Hold 1Sell 0Strong Sell 0

Latest SEC Filings

ONC's most recent filings, straight from SEC EDGAR. Annual and quarterly reports are the deep dives; 8-Ks flag material events the moment they happen. How to read a 10-K

In the Idea Lab

ONC — frequently asked questions

Is ONC a good stock to buy?

We don't give buy or sell advice. Our model rates BeOne Medicines AG Neutral (48/100) based on its growth, profitability, financial health, and valuation — use that as a research starting point and make your own decision.

What is ONC's rating on The Stocks School?

BeOne Medicines AG currently scores 48/100 (Neutral) on our transparent model, which weighs real fundamentals: growth, margins, returns on capital, balance-sheet strength, and valuation.

How our ratings work →
Where does ONC's data come from?

Live price data plus real fundamentals and 5-year financials pulled directly from BeOne Medicines AG's SEC filings — refreshed automatically, not hand-entered.

How is the 5-year projection for ONC calculated?

It's a scenario model. It starts from the latest annual revenue and net margin in SEC filings, grows revenue at an assumed rate (trailing revenue growth by default), and applies a P/E range built around today's multiple to show the resulting share-price range. When a stock has no growth or P/E data, the starting values are placeholders. It's a tool for thinking, not a prediction.

Is this ONC analysis financial advice?

No. Everything on this page is educational research, not financial advice or a recommendation to buy or sell ONC. Always do your own research and consider a licensed professional.

Data notice. Fundamentals and financial statements are sourced from company filings (SEC EDGAR) and market-data providers; prices and market caps refresh on trading days and may be delayed. Ratings, projections, technical signals, and written summaries are model- or rule-generated for education and may simplify or lag the latest filings.

Not advice. Nothing on this page is investment advice or a recommendation to buy, hold, or sell any security. Do your own research and consult a licensed financial professional before investing.